Hi Krishna,
As i have mentioned that the the SAPOSS rfc is working fine with the other 3 Sap Instances which has been installed in the same server, getting issue only with one instance.
Could you confirm for any other software is running on the server ? If yes then as per dev_w3 findings & from the error screen
10053 Software caused connection abort can occur
try to refer SAP KBA 1192632 - Error: 10053 Software caused connection abort - Data Quality XI
to allow the relevant ports & as well as try to disable any antivirus or firewall on the system to check again.
Hope this will help you.
Regards,